Validity of neuron-specific enolase as a prognostic tool in acute ischemic stroke in adults at Suez Canal University Hospital

Abstract Background Biological markers of acute nerve cell damage can assist in the outcome ischemic stroke, such as neuron-specific enolase (NSE) that have been tested for association with initial severity extent infarction, and functional outcome. Objective To determine short-term prognostic value biochemical marker stroke. Methods A cohort study carried out on 37 patients Data were gathered a prepared data sheet. Initial serum NSE level was measured to Emergency department within 6 h onset stroke another measurement after 48 h. National Institute Health Stroke Scale (NIHSS) held at presentation 28 days morbidity mortality. Results Out patients, 31 survived (no-death group) died (death group). The mean significantly higher death group than no-death group. There statistically significant positive correlation between clinical among ( r = 0.737, p 0.000). Conclusion Neuron-specific be applied single independent prediction mortality patients.